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IPIC has established itself as one of the leading international congresses on Primary Immunodeficiencies (PID) clinical care with a unique approach to its scientific programme underpinned by its focus on patient-centeredness. With a truly international impact, the congress has earned its definite place and role in the PID clinical landscape. The CME-accredited clinical programme of IPIC is designed to complement other existing PID international congresses and regional scientific meetings. The IPIC2027 Programme will feature international key opinion leaders in the field and seek to engage international delegates in thought-provoking and interactive sessions. Key topics will include, among others: Newborn Screening, Management of Neurological manifestations in PIDs, Transplantation challenges in PIDs, Cancer and immunity, Ethical considerations, Discussion of complex cases of PIDs, Clinical development of PIDs.